| San Antonio Spurs Rankings 2021-2022 | Stats Glossary  |
| Games with 121 or more Efficiency Recap | San Antonio Spurs Record : 29 - 25 |
| No | Date | Game | Score | Efficiency Recap |
| 1 | Apr 10 | at Dallas | L | 120-130 | 127 |
| 2 | Apr 7 | at Minnesota | L | 121-127 | 127 |
| 3 | Apr 5 | at Denver | W | 116-97 | 127 |
| 4 | Apr 3 | vs Portland | W | 113-92 | 127 |
| 5 | Apr 1 | vs Portland | W | 130-111 | 127 |
| 6 | Mar 30 | vs Memphis | L | 111-112 | 125 |
| 7 | Mar 28 | at Houston | W | 123-120 | 127 |
| 8 | Mar 26 | at New_Orleans | W | 107-103 | 122 |
| 9 | Mar 23 | at Portland | W | 133-96 | 127 |
| 10 | Mar 16 | vs Oklahoma_City | W | 122-120 | 127 |
| 11 | Mar 14 | vs Minnesota | L | 139-149 | 127 |
| 12 | Mar 12 | vs Indiana | L | 108-119 | 124 |
| 13 | Mar 7 | vs L.A.Lakers | W | 117-110 | 127 |
| 14 | Mar 5 | at Charlotte | L | 117-123 | 127 |
| 15 | Mar 3 | vs Sacramento | L | 112-115 | 126 |
| 16 | Feb 26 | at Miami | L | 129-133 | 127 |
| 17 | Feb 25 | at Washington | W | 157-153 | 127 |
| 18 | Feb 16 | at Oklahoma_City | W | 114-106 | 127 |
| 19 | Feb 12 | at New_Orleans | W | 124-114 | 127 |
| 20 | Feb 11 | at Atlanta | W | 136-121 | 127 |
| 21 | Feb 4 | vs Houston | W | 131-106 | 127 |
| 22 | Feb 1 | vs Golden_State | L | 120-124 | 127 |
| 23 | Jan 30 | at Phoenix | L | 110-115 | 122 |
| 24 | Jan 28 | vs Chicago | W | 131-122 | 127 |
| 25 | Jan 26 | vs Memphis | L | 110-118 | 127 |
| 26 | Jan 25 | at Houston | W | 134-104 | 127 |
| 27 | Jan 23 | vs Philadelphia | L | 109-115 | 127 |
| 28 | Jan 19 | vs Oklahoma_City | W | 118-96 | 127 |
| 29 | Jan 14 | vs Cleveland | L | 109-114 | 121 |
| 30 | Jan 12 | vs Houston | L | 124-128 | 127 |
| 31 | Jan 9 | at Brooklyn | L | 119-121 | 127 |
| 32 | Jan 1 | at Detroit | L | 116-117 | 121 |
| 33 | Dec 26 | vs Detroit | W | 144-109 | 127 |
| 34 | Dec 23 | at L.A.Lakers | W | 138-110 | 127 |
| 35 | Dec 20 | at L.A.Clippers | W | 116-92 | 127 |
| 36 | Dec 19 | at Sacramento | L | 114-121 | 127 |
| 37 | Dec 17 | at Utah | W | 128-126 | 127 |
| 38 | Dec 15 | vs Charlotte | L | 115-131 | 127 |
| 39 | Dec 12 | vs New_Orleans | W | 112-97 | 127 |
| 40 | Dec 9 | vs Denver | W | 123-111 | 127 |
| 41 | Dec 7 | vs New_York | L | 109-121 | 125 |
| 42 | Dec 4 | at Golden_State | W | 112-107 | 127 |
| 43 | Dec 2 | at Portland | W | 114-83 | 127 |
| 44 | Nov 29 | vs Washington | W | 116-99 | 127 |
| 45 | Nov 22 | vs Phoenix | L | 111-115 | 124 |
| 46 | Nov 12 | vs Dallas | L | 109-123 | 124 |
| 47 | Nov 10 | vs Sacramento | W | 136-117 | 127 |
| 48 | Nov 5 | at Orlando | W | 102-89 | 126 |
| 49 | Nov 3 | vs Dallas | L | 108-109 | 127 |
| 50 | Nov 1 | at Indiana | L | 118-131 | 127 |
| 51 | Oct 30 | at Milwaukee | W | 102-93 | 122 |
| 52 | Oct 26 | vs L.A.Lakers | L | 121-125 | 127 |
| 53 | Oct 23 | vs Milwaukee | L | 111-121 | 127 |
| 54 | Oct 20 | vs Orlando | W | 123-97 | 127 |
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